1639040-95-1

pan-HER-IN-2 Chemical Structure
1639040-95-1

Chemical Structure

pan-HER-IN-2

  • CAS No.: 1639040-95-1
  • Formula:C19H15BrClN5O
  • Molecular Weight:444.71

IUPAC Name: N-(4-((3-bromo-1H-indol-5-yl)amino)quinazolin-6-yl)-3-chloropropanamide

InChIKey: WTWFBKFNVCFROY-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C2N=CN=C(C2=C1)NC3=CC4=C(NC=C4Br)C=C3)CCCl

Biological Activity: pan-HER-IN-2 (Compound C6) is a reversible, orally active pan-HER inhibitor with IC50 values of 0.72, 2.0, 8.2 and 75.1 nM against EGFR, HER4, EGFRT790M/L858R and HER2, respectively. pan-HER-IN-2 induces apoptosis and shows antitumor activities[1].

Cat. No. Product Name Purity Description Pricing
HY-144677 		pan-HER-IN-2 98.10% pan-HER-IN-2 (Compound C6) is a reversible, orally active pan-HER inhibitor with IC50 values of 0.72, 2.0, 8.2 and 75.1 nM against EGFR, HER4, EGFRT790M/L858R and HER2, respectively. pan-HER-IN-2 induces apoptosis and shows antitumor activities.
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

Pricing 
Expand Hide
References

Keywords