167006-13-5
167006-13-5
Chemical Structure
KRH-594
- CAS No.: 167006-13-5
- Formula:C25H23N7O3S
- Molecular Weight:501.56
IUPAC Name: (Z)-2-((3-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene)carbamoyl)cyclopent-1-ene-1-carboxylic acid
InChIKey: UFZKNCXXIFQTNB-QPLCGJKRSA-N
SMILES: O=C(C1=C(C(/N=C2SC(CC)=NN\2CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)=O)CCC1)O
Biological Activity: KRH-594 is an orally active angiotensin AT1 receptor antagonist. KRH-594 ameliorates the progression of diabetic nephropathy and hyperlipidaemia. KRH-594 inhibits cardiac hypertrophy[1].
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KRH-594 | KRH-594 is an orally active angiotensin AT1 receptor antagonist. KRH-594 ameliorates the progression of diabetic nephropathy and hyperlipidaemia. KRH-594 inhibits cardiac hypertrophy. | |||||||||||||||||||||
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References
Keywords
