1683535-53-6
Chemical Structure
Apcin-A monohydrochloride
- CAS No.: 1683535-53-6
- Formula:C10H15Cl4N5O2
- Molecular Weight:379.07
IUPAC Name: 3-aminopropyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate hydrochloride
InChIKey: NEYHFUCNZUYAJK-UHFFFAOYSA-N
SMILES: O=C(NC(C(Cl)(Cl)Cl)NC1=NC=CC=N1)OCCCN.Cl
Biological Activity: Apcin-A monohydrochloride, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A monohydrochloride interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A monohydrochloride can be used to synthesize the PROTAC CP5V (HY-130257)[1].
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Apcin-A monohydrochloride | Apcin-A monohydrochloride, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A monohydrochloride interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A monohydrochloride can be used to synthesize the PROTAC CP5V (HY-130257). | |||||||||||||||||||||
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Keywords