184302-49-6
184302-49-6
Chemical Structure
FF-10502
- CAS No.: 184302-49-6
- Formula:C9H12FN3O3S
- Molecular Weight:261.27
IUPAC Name: 4-amino-1-((2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidin-2(1H)-one
InChIKey: NIDPJRZOVFIBQB-PXBUCIJWSA-N
SMILES: O=C1N([C@@H]2S[C@H](CO)[C@@H](O)[C@@H]2F)C=CC(N)=N1
Biological Activity: FF-10502, a structural analog of Gemcitabine, is a pyrimidine nucleoside antimetabolite. FF-10502 inhibits DNA polymerase α and β. FF-10502 shows beneficial anticancer activity via a mechanism of action on dormant cells[1].
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FF-10502 | FF-10502, a structural analog of Gemcitabine, is a pyrimidine nucleoside antimetabolite. FF-10502 inhibits DNA polymerase α and β. FF-10502 shows beneficial anticancer activity via a mechanism of action on dormant cells. | |||||||||||||||||||||
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References
Keywords
