186611-44-9
186611-44-9
Chemical Structure
Tripolin B
- CAS No.: 186611-44-9
- Formula:C12H9N3O
- Molecular Weight:211.22
IUPAC Name: (Z)-3-((1H-imidazol-5-yl)methylene)indolin-2-one
InChIKey: VEEGZPWAAPPXRB-YHYXMXQVSA-N
SMILES: O=C1NC2=C(C=CC=C2)/C1=C/C3=CN=CN3
Biological Activity: Tripolin B is an ATP-competitive Aurora kinase inhibitor with IC50 values of 2.5 µM and 6 µM for Aurora A and Aurora B kinases, respectively. Tripolin B does not inhibit Aurora kinase in cells[1].
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Tripolin B | Tripolin B is an ATP-competitive Aurora kinase inhibitor with IC50 values of 2.5 µM and 6 µM for Aurora A and Aurora B kinases, respectively. Tripolin B does not inhibit Aurora kinase in cells. | |||||||||||||||||||||
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References
Keywords
