191163-45-8
Chemical Structure
4-Azide-TFP-amide-SS-propionic acid
- CAS No.: 191163-45-8
- Formula:C12H10F4N4O3S2
- Molecular Weight:398.36
InChIKey: WGVMMTKVRGZTAV-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NC1=C(C(F)=C(C(F)=C1F)C(NCCSSCCC(O)=O)=O)F
Biological Activity: 4-Azide-TFP-Amide-SS-propionic acid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond. The disulfide bond can be cleaved via reducing agents.
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4-Azide-TFP-amide-SS-propionic acid | 4-Azide-TFP-Amide-SS-propionic acid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond. The disulfide bond can be cleaved via reducing agents. | |||||||||||||||||||||
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Keywords
