19395-41-6
Chemical Structure
Ritalinic acid
Synonym(s): Ritalinate
- CAS No.: 19395-41-6
- Formula:C13H17NO2
- Molecular Weight:219.28
IUPAC Name: 2-phenyl-2-(piperidin-2-yl)acetic acid
InChIKey: INGSNVSERUZOAK-UHFFFAOYSA-N
SMILES: C2=C(C(C1CCCCN1)C(O)=O)C=CC=C2
Biological Activity: Ritalinic acid (Ritalinate) is a metabolite of Methylphenidate. Ritalinic acid has no biological activity or only extremely low biological activity. The concentration of Ritalinic acid detected in university campus sewage shows a gradual upward trend in the first semester, while no obvious periodic variation pattern related to academic stress is observed in the second semester. Ritalinic acid can be used in studies related to attention deficit disorder, narcolepsy, depression and attention deficit hyperactivity disorder[1][2][3][4].
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Ritalinic acid | 99.81% | Ritalinic acid (Ritalinate) is a metabolite of Methylphenidate. Ritalinic acid has no biological activity or only extremely low biological activity. The concentration of Ritalinic acid detected in university campus sewage shows a gradual upward trend in the first semester, while no obvious periodic variation pattern related to academic stress is observed in the second semester. Ritalinic acid can be used in studies related to attention deficit disorder, narcolepsy, depression and attention deficit hyperactivity disorder. | ||||||||||||||||||||
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- [1]. Markowitz JS, et al. Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol. Drug Metab Dispos. 2000;28(6):620-624. [Content Brief]
- [2]. del Mar Ramirez Fernandez M, et al. Liquid chromatography-tandem mass spectrometry method for the simultaneous analysis of multiple hallucinogens, chlorpheniramine, ketamine, ritalinic acid, and metabolites, in urine. J Anal Toxicol. 2007;31(8):497-504. [Content Brief]
- [3]. Letzel M, et al. Occurrence and fate of the human pharmaceutical metabolite ritalinic acid in the aquatic system. Chemosphere. 2010;81(11):1416-1422. [Content Brief]
- [4]. Burgard DA, et al. Potential trends in Attention Deficit Hyperactivity Disorder (ADHD) drug use on a college campus: wastewater analysis of amphetamine and ritalinic acid. Sci Total Environ. 2013;450-451:242-249. [Content Brief]
Keywords
