2130040-60-5
Chemical Structure
Anticancer agent 245
- CAS No.: 2130040-60-5
- Formula:C24H22BNO4
- Molecular Weight:399.25
InChIKey: KANKQAZGSKQFCK-UHFFFAOYSA-N
SMILES: O=C(CCC1=C(B(OC2)O)C2=CC=C1)NC3=CC(C4=CC=C(C(C)=O)C=C4)=CC=C3
Biological Activity: Anticancer agent 245 (Compound 115) inhibits proliferation of cancer cell SKOV3, MDA-MB-231 and HCT-116 with IC50 of 0.021, 0.056 and 0.11 μM, respectively. Anticancer agent 245 exhibits antitumor efficacy in mice and good pharmacokinetic characteristics in rat models[1].
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Anticancer agent 245 | Anticancer agent 245 (Compound 115) inhibits proliferation of cancer cell SKOV3, MDA-MB-231 and HCT-116 with IC50 of 0.021, 0.056 and 0.11 μM, respectively. Anticancer agent 245 exhibits antitumor efficacy in mice and good pharmacokinetic characteristics in rat models. | |||||||||||||||||||||
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Keywords