21401-21-8
Chemical Structure
Taxiphyllin
Synonym(s): (2R)-Taxiphyllin
- CAS No.: 21401-21-8
- Formula:C14H17NO7
- Molecular Weight:311.29
IUPAC Name: (R)-2-(4-hydroxyphenyl)-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile
InChIKey: NVLTYOJHPBMILU-GMDXDWKASA-N
SMILES: N#C[C@@H](C(C=C1)=CC=C1O)O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO
Biological Activity:
Taxiphyllin (2R-Taxiphyllin) is a plant cyanogenic glycoside, which exhibits inhibitory activity for tyrosinase[2]. Taxiphyllin exhibits cytotoxicity in BRL-3A cellls with an IC50 of 18.75 μm[3] and antimicrobial activities against Staphylococcus aureus with an EC50 of 0.96 μM[4].
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Taxiphyllin | Taxiphyllin (2R-Taxiphyllin) is a plant cyanogenic glycoside, which exhibits inhibitory activity for tyrosinase. Taxiphyllin exhibits cytotoxicity in BRL-3A cellls with an IC50 of 18.75 μm and antimicrobial activities against Staphylococcus aureus with an EC50 of 0.96 μM. |
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- [2]. Wu B. Tyrosinase inhibitors from terrestrial and marine resources. Curr Top Med Chem. 2014;14(12):1425-49. [Content Brief]
- [3]. Yi JJ, et al., Characterisation and in vitro cytotoxicity of toxic and degradation compounds in bamboo shoots (Dendrocalamus Sinicus) during traditional fermentation. Int J of Food Sci Tech. 2020
- [4]. Oueslati MH, et al., Phytochemical constituents from Salsola tetrandra. J Nat Prod. 2006 Sep;69(9):1366-9. [Content Brief]
Keywords
