2205846-49-5
2205846-49-5
Chemical Structure
BMS905
- CAS No.: 2205846-49-5
- Formula:C23H29N3
- Molecular Weight:347.50
IUPAC Name: 2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperidin-4-yl)-1H-indole
InChIKey: XSXCQWXAFRASGU-UHFFFAOYSA-N
SMILES: CC1=NC(C)=CC(C2=C(C(C)C)C3=C(C=CC(C4CCNCC4)=C3)N2)=C1
Biological Activity: BMS905 is an orally active TLR7 and TLR8 dual inhibitor (IC50s: 0.7 and 3.2 nM respectively). BMS905 inhibits TLR7 or TLR8 induced IL-6 production in human/mouse whole blood. BMS905 can be used for research of lupus[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BMS905 | 98.25% | BMS905 is an orally active TLR7 and TLR8 dual inhibitor (IC50s: 0.7 and 3.2 nM respectively). BMS905 inhibits TLR7 or TLR8 induced IL-6 production in human/mouse whole blood. BMS905 can be used for research of lupus. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
