2303917-78-2
Chemical Structure
Cap-dependent endonuclease-IN-2
- CAS No.: 2303917-78-2
- Formula:C30H24FN3O7S
- Molecular Weight:589.59
IUPAC Name: N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(2-phenoxyphenyl)pyrimidin-2-yl)amino)phenyl)acrylamide
InChIKey: HNRKICHGGJTDAV-JWQCQUIFSA-N
SMILES: COC(OCOC1=C2N(C=CC1=O)N([C@@]3([H])N(CCOC3)C2=O)[C@@]4([H])C5=CC=C(F)C=C5C6=C(SC=C6)C7=CC=CC=C74)=O
Biological Activity: Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-2 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-2 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent WO2019052565A1, compound 28)[1].
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Cap-dependent endonuclease-IN-2 | Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-2 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-2 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent WO2019052565A1, compound 28). | |||||||||||||||||||||
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Keywords
