2306193-95-1
Chemical Structure
(S,S,S)-VH032-cyclopropane-F
- CAS No.: 2306193-95-1
- Formula:C26H33FN4O5S
- Molecular Weight:532.63
IUPAC Name: (2S,4S)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: OKBLHQUBMCCFKE-BBTUJRGHSA-N
SMILES: OC1=C(CNC([C@H]2N(C([C@@H](NC(C3(F)CC3)=O)C(C)(C)C)=O)C[C@@H](O)C2)=O)C=CC(C4=C(N=CS4)C)=C1
Biological Activity: (S,S,S)-VH032-cyclopropane-F is a ligand for E3 ubiquitin ligases. (S,S,S)-VH032-cyclopropane-F can be linked to target protein ligands via a linker to form the PROTAC cis-VZ185 (HY-114322A)[1].
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(S,S,S)-VH032-cyclopropane-F | (S,S,S)-VH032-cyclopropane-F is a ligand for E3 ubiquitin ligases. (S,S,S)-VH032-cyclopropane-F can be linked to target protein ligands via a linker to form the PROTAC cis-VZ185 (HY-114322A). | |||||||||||||||||||||
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Keywords
