2408801-88-5
Chemical Structure
YU253434
- CAS No.: 2408801-88-5
- Formula:C27H26N8O12S
- Molecular Weight:686.61
InChIKey: NDBWOXXNCCSABA-JFLUISNFSA-N
SMILES: OC(C1=C(C(NCCN2C(C3=CC(O)=C(O)C=C3C2=O)=O)=O)CN(C[C@@H]4NC(/C(C5=CSC(N)=N5)=N\OC(C)(C)C(O)=O)=O)N1C4=O)=O
Biological Activity: YU253434 is a PBP3 inhibitor with an IC50 of 2.5 μM against Pseudomonas aeruginosa PBP3. YU253434 contains a siderophore domain that facilitates its uptake into the periplasmic space of Gram-negative bacilli. YU253434 exhibits antibacterial activity against multidrug-resistant Gram-negative bacilli. YU253434 can be used in studies of multidrug-resistant Gram-negative bacterial infections[1].
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YU253434 | YU253434 is a PBP3 inhibitor with an IC50 of 2.5 μM against Pseudomonas aeruginosa PBP3. YU253434 contains a siderophore domain that facilitates its uptake into the periplasmic space of Gram-negative bacilli. YU253434 exhibits antibacterial activity against multidrug-resistant Gram-negative bacilli. YU253434 can be used in studies of multidrug-resistant Gram-negative bacterial infections. | |||||||||||||||||||||
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Keywords
