2410793-22-3
Chemical Structure
GRK5-IN-3
- CAS No.: 2410793-22-3
- Formula:C23H21N7O3
- Molecular Weight:443.46
IUPAC Name: 2-((2-((4-acrylamido-2-methoxyphenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide
InChIKey: PYFNYNPQSUXBGV-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(OC)=C1)NC2=NC(NC3=C(C(N)=O)C=CC=C3)=C4C=CNC4=N2)C=C
Biological Activity: GRK5-IN-3 is a covalent inhibitor of GRK5 (G Protein-Coupled Receptor Kinase 5). GRK5-IN-3 shows potent inhibitory effect to GRK5 and GRK6 with IC50s of 0.22 μM and 0.41 μM, respectively[1].
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GRK5-IN-3 | GRK5-IN-3 is a covalent inhibitor of GRK5 (G Protein-Coupled Receptor Kinase 5). GRK5-IN-3 shows potent inhibitory effect to GRK5 and GRK6 with IC50s of 0.22 μM and 0.41 μM, respectively. | |||||||||||||||||||||
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Keywords