2417012-26-9
Chemical Structure
WDR5-IN-5
- CAS No.: 2417012-26-9
- Formula:C29H29F3N6O
- Molecular Weight:534.58
IUPAC Name: (S)-7-((1H-imidazol-1-yl)methyl)-2-(cyclopropyl(4-methylpyridin-2-yl)methyl)-5-(1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one
InChIKey: FFUQRXFVTVBZMZ-SANMLTNESA-N
SMILES: O=C1N([C@@H](C2CC2)C3=NC=CC(C)=C3)CCC4=C1C=C(CN5C=CN=C5)C=C4C6=CN(CC)N=C6C(F)(F)F
Biological Activity: WDR5-IN-5 is an orally active and selective inhibitor of WIN site of WD repeat domain 5 (WDR5). WDR5-IN-5 exhibits anti-proliferative activity towards cancer cells and good pharmacokinetics profile in mice. WDR5-IN-5 shows high affinity to WDR5 and the binding affinity Ki value <0.02 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WDR5-IN-5 | 99.56% | WDR5-IN-5 is an orally active and selective inhibitor of WIN site of WD repeat domain 5 (WDR5). WDR5-IN-5 exhibits anti-proliferative activity towards cancer cells and good pharmacokinetics profile in mice. WDR5-IN-5 shows high affinity to WDR5 and the binding affinity Ki value <0.02 nM. | ||||||||||||||||||||
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Keywords
