2448475-19-0
2448475-19-0
Chemical Structure
(R)-VX-984
Synonym(s): (R)-M9831
- CAS No.: 2448475-19-0
- Formula:C23H21D2N7O
- Molecular Weight:415.49
IUPAC Name: (R)-N-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl-4',6'-d2)amino)propan-2-yl)quinoline-4-carboxamide
InChIKey: PEACIOGDEQRHFA-WXFXTCFHSA-N
SMILES: O=C(C1=CC=NC2=C([C@@H](C)CNC3=CC(C4=C([2H])N=C(C)N=C4[2H])=NC=N3)C=CC=C12)NC
Biological Activity: (R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent DNA-PK inhibitor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(R)-VX-984 | 99.88% | (R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent DNA-PK inhibitor. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
VX-984 | 99.47% | VX-984 is an orally active, potent, selective and BBB-penetrated DNA-PK inhibitor. VX-984 efficiently inhibits NHEJ (non-homologous end joining) and increases DSBs (DNA double-strand breaks). VX-984 can be used for glioblastomas (GBM) and non-small cell lung cancer (NSCLC) research. VX-984 is a de novo deuterium. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
