2485779-34-6
Chemical Structure
ATX inhibitor 13
- CAS No.: 2485779-34-6
- Formula:C31H35Cl2N5O3
- Molecular Weight:596.55
IUPAC Name: 3,5-dichlorobenzyl (2-ethyl-6-(4-((4-(2-hydroxyethyl)piperazin-1-yl)methyl)phenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)carbamate
InChIKey: NSFSOTZMNUYMAK-UHFFFAOYSA-N
SMILES: O=C(OCC1=CC(Cl)=CC(Cl)=C1)NC2=C(CC)N=C3C(C)=CC(C4=CC=C(CN5CCN(CCO)CC5)C=C4)=CN32
Biological Activity: ATX inhibitor 13 (10c) is an orally active and potent ATX inhibitor, with an IC50 of 3.4 nM. ATX inhibitor 13 inhibits proliferation and migration, and induces apoptosis and G2 phase arrest in RAW264.7 cells. ATX inhibitor 13 suppresses tumor cell colony formation[1].
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ATX inhibitor 13 | ATX inhibitor 13 (10c) is an orally active and potent ATX inhibitor, with an IC50 of 3.4 nM. ATX inhibitor 13 inhibits proliferation and migration, and induces apoptosis and G2 phase arrest in RAW264.7 cells. ATX inhibitor 13 suppresses tumor cell colony formation. | |||||||||||||||||||||
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Keywords