2488761-07-3
Chemical Structure
Thalidomide-NH-PEG8-Ts
- CAS No.: 2488761-07-3
- Formula:C36H49N3O14S
- Molecular Weight:779.85
IUPAC Name: 23-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15,18,21-heptaoxatricosyl 4-methylbenzenesulfonate
InChIKey: GZOHJVDFMQTYJD-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(C4=CC=C(C)C=C4)=O)=O
Biological Activity: Thalidomide-NH-PEG8-Ts is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 8-unit PEG linker used in PROTAC technology, such as IDO1 PROTAC degrader (HY-131911)[1].
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Thalidomide-NH-PEG8-Ts | Thalidomide-NH-PEG8-Ts is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 8-unit PEG linker used in PROTAC technology, such as IDO1 PROTAC degrader (HY-131911). | |||||||||||||||||||||
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Keywords
