2494010-42-1
Chemical Structure
SHR2415
- CAS. Nr.: 2494010-42-1
- Formula:C23H22ClN7O2
- Molecular Weight:463.92
IUPAC Name: (S)-2-(1-(3-chlorophenyl)-2-hydroxyethyl)-6-(5-methyl-2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-1,2-dihydro-3H-pyrrolo[1,2-c]imidazol-3-one
InChIKey: WKBMRZDYCZPLFO-LJQANCHMSA-N
SMILES: CC1=CN=C(N=C1C2=CN3C(N(CC3=C2)[C@@H](C4=CC(Cl)=CC=C4)CO)=O)NC5=CC=NN5C
Biological Activity: SHR2415 is a highly potent, selective and orally active ERK1/2 inhibitor. SHR2415 has inhibition activity for ERK1 and ERK2 with IC50 values of 2.8 nM and 5.9 nM, respectively. SHR2415 exhibits high potency with an IC50 value of 44.6 nM in Colo205 cells. SHR2415 can be used for the research of cancer[1].
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SHR2415 | 98.04% | SHR2415 is a highly potent, selective and orally active ERK1/2 inhibitor. SHR2415 has inhibition activity for ERK1 and ERK2 with IC50 values of 2.8 nM and 5.9 nM, respectively. SHR2415 exhibits high potency with an IC50 value of 44.6 nM in Colo205 cells. SHR2415 can be used for the research of cancer. | ||||||||||||||||||||
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Keywords
