252025-48-2
252025-48-2
Chemical Structure
AF-2785
- CAS No.: 252025-48-2
- Formula:C17H12Cl2N2O2
- Molecular Weight:347.20
IUPAC Name: (Z)-3-(1-(2,4-dichlorobenzyl)-1H-indazol-3-yl)acrylic acid
InChIKey: JXBHFVLHFJMKPK-FPLPWBNLSA-N
SMILES: O=C(O)/C=C\C1=NN(CC2=C(Cl)C=C(Cl)C=C2)C3=CC=CC=C31
Biological Activity: AF-2785 is a potent CFTR blocker. AF-2785 inhibits the cAMP-activated chloride current in rat epididymal cells with an IC50 of 170.6 μM. AF-2785 can be used in research related to contraceptives[1].
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AF-2785 | AF-2785 is a potent CFTR blocker. AF-2785 inhibits the cAMP-activated chloride current in rat epididymal cells with an IC50 of 170.6 μM. AF-2785 can be used in research related to contraceptives. | |||||||||||||||||||||
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References
Keywords
