2521770-35-2
Chemical Structure
Anticancer agent 70
- CAS. Nr.: 2521770-35-2
- Formula:C13H9Cl2N3O2S
- Molecular Weight:342.20
IUPAC Name: 2,4-dichloro-N-(1H-indazol-7-yl)benzenesulfonamide
InChIKey: URDFXYJXTZQRSU-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(Cl)C=C1Cl)(NC2=CC=CC3=C2NN=C3)=O
Biological Activity: Anticancer agent 70 (Compound 21), an anticancer agent, exhibits remarkable cytotoxic activity against numerous human cancer cell lines. Anticancer agent 70 results in the G0/G1-cell cycle arrest with a concomitant increase in p53 and p21 protein levels. Anticancer agent 70 leads to ATP depletion and disruption of the mitochondrial membrane potential[1].
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Anticancer agent 70 | Anticancer agent 70 (Compound 21), an anticancer agent, exhibits remarkable cytotoxic activity against numerous human cancer cell lines. Anticancer agent 70 results in the G0/G1-cell cycle arrest with a concomitant increase in p53 and p21 protein levels. Anticancer agent 70 leads to ATP depletion and disruption of the mitochondrial membrane potential. | |||||||||||||||||||||
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Keywords