2649362-71-8
Chemical Structure
Cap-dependent endonuclease-IN-17
- CAS No.: 2649362-71-8
- Formula:C24H20F2N3O7PS
- Molecular Weight:563.47
IUPAC Name: (R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl dihydrogen phosphate
InChIKey: RBPQWOONNOYHLF-CTNGQTDRSA-N
SMILES: O=C1N2[C@](COCC2)([H])N([C@@H]3C4=CC=CC=C4SCC5=C(F)C(F)=CC=C35)N6C1=C(OP(O)(O)=O)C(C=C6)=O
Biological Activity: Cap-dependent endonuclease-IN-17 is a cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-17 shows antiviral activity against influenza virus A/Hanfang/359/95 (H3N2) with IC50 of 1.29 μM (CN112898346A; DSC701)[1].
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Cap-dependent endonuclease-IN-17 | Cap-dependent endonuclease-IN-17 is a cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-17 shows antiviral activity against influenza virus A/Hanfang/359/95 (H3N2) with IC50 of 1.29 μM (CN112898346A; DSC701). | |||||||||||||||||||||
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Keywords