2660129-56-4
Chemical Structure
KRAS G12C inhibitor 38
- CAS No.: 2660129-56-4
- Formula:C38H43F3N8O2
- Molecular Weight:700.80
IUPAC Name: 1-(7-(6-cyclopropyl-7-(5-methyl-1H-indazol-4-yl)-2-(3-(pyrrolidin-1-yl)azetidin-1-yl)-8-(2,2,2-trifluoroethoxy)quinazolin-4-yl)-2,7-diazaspiro[3.5]nonan-2-yl)prop-2-en-1-one
InChIKey: PBENVJNCTVARNW-UHFFFAOYSA-N
SMILES: O=C(N1CC2(CCN(CC2)C3=NC(N4CC(C4)N5CCCC5)=NC6=C(C(C7=C8C=NNC8=CC=C7C)=C(C9CC9)C=C63)OCC(F)(F)F)C1)C=C
Biological Activity: KRAS G12C inhibitor 38 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 38 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129820A1, compound 171)[1].
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KRAS G12C inhibitor 38 | KRAS G12C inhibitor 38 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 38 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129820A1, compound 171). | |||||||||||||||||||||
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Keywords