2691174-27-1
2691174-27-1
Chemical Structure
BBDDL2059
- CAS No.: 2691174-27-1
- Formula:C27H36N4O4S
- Molecular Weight:512.66
InChIKey: BKTRXKQBQKZJJS-UHFFFAOYSA-N
SMILES: O=C(C1=CC(CNC(C=C)=O)=CC(N(C2CCOCC2)CC)=C1C)NCC3=C(C=C(NC3=O)C)SC
Biological Activity: BBDDL2059 is a selective covalent inhibitor of histone methyltransferase EZH2 with an IC50 of 1.5 nM for EZH2-Y641F. BBDDL2059 inhibits lymphoma cell growth at nanomolar concentrations and can be used for anticancer research[1].
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BBDDL2059 | BBDDL2059 is a selective covalent inhibitor of histone methyltransferase EZH2 with an IC50 of 1.5 nM for EZH2-Y641F. BBDDL2059 inhibits lymphoma cell growth at nanomolar concentrations and can be used for anticancer research. | |||||||||||||||||||||
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References
Keywords
