2716956-47-5
Chemical Structure
SOS1-IN-5
- CAS No.: 2716956-47-5
- Formula:C26H31F3N4O5
- Molecular Weight:536.54
IUPAC Name: (R)-N-(1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-2-methyl-7,8,10,11,13,14,16,17-octahydro-[1,4,7,10,13]pentaoxacyclopentadecino[2,3-g]quinazolin-4-amine
InChIKey: GEZMTRWNCBYKCP-MRXNPFEDSA-N
SMILES: C[C@H](C1=CC(C(F)(F)F)=CC(N)=C1)NC2=NC(C)=NC3=C2C=C(OCCOCCOCCOCCO4)C4=C3
Biological Activity: SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)[1].
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SOS1-IN-5 | SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4). | |||||||||||||||||||||
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Keywords
