2738392-83-9
Chemical Structure
SOS1-IN-4
- CAS No.: 2738392-83-9
- Formula:C24H29F2N4O2P
- Molecular Weight:474.48
IUPAC Name: (R)-1-(4-((1-(3-amino-5-(difluoromethyl)phenyl)ethyl)amino)-7-methoxy-2-methylquinazolin-6-yl)phosphinane 1-oxide
InChIKey: AYUPAZPTYFGDHL-CQSZACIVSA-N
SMILES: COC1=CC2=NC(C)=NC(N[C@H](C)C3=CC(N)=CC(C(F)F)=C3)=C2C=C1P4(CCCCC4)=O
Biological Activity: SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65)[1].
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SOS1-IN-4 | SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65). | |||||||||||||||||||||
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Keywords