2738392-83-9

SOS1-IN-4 Chemical Structure
2738392-83-9

Chemical Structure

SOS1-IN-4

  • CAS No.: 2738392-83-9
  • Formula:C24H29F2N4O2P
  • Molecular Weight:474.48

IUPAC Name: (R)-1-(4-((1-(3-amino-5-(difluoromethyl)phenyl)ethyl)amino)-7-methoxy-2-methylquinazolin-6-yl)phosphinane 1-oxide

InChIKey: AYUPAZPTYFGDHL-CQSZACIVSA-N

SMILES: COC1=CC2=NC(C)=NC(N[C@H](C)C3=CC(N)=CC(C(F)F)=C3)=C2C=C1P4(CCCCC4)=O

Biological Activity: SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65)[1].

Cat. No. Product Name Purity Description Pricing
HY-145047
SOS1-IN-4 SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65).
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