2761446-55-1
Chemical Structure
Deg-1
- CAS No.: 2761446-55-1
- Formula:C15H27N5O5
- Molecular Weight:357.41
InChIKey: INBZJGUSXQXYEH-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCOCCOCCOCCOCCN1C=NC=C1
Biological Activity: Deg-1 is a bifunctional probe with a cleavage group and a covalent binding group. Deg-1 binds covalently to target nucleic acids and acts as a click degrader to cleave nucleic acid molecules, exhibiting the potential to selectively cleave target nucleic acids intracellularly. Deg-1 contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkynyl groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN. Deg-1 can be used in studies related to acute myeloid leukemia and RNA function[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Deg-1 | 99.45% | Deg-1 is a bifunctional probe with a cleavage group and a covalent binding group. Deg-1 binds covalently to target nucleic acids and acts as a click degrader to cleave nucleic acid molecules, exhibiting the potential to selectively cleave target nucleic acids intracellularly. Deg-1 contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkynyl groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN. Deg-1 can be used in studies related to acute myeloid leukemia and RNA function. | ||||||||||||||||||||
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