2765304-82-1
2765304-82-1
Chemical Structure
NMS-0963
- CAS No.: 2765304-82-1
- Formula:C23H29N7O3
- Molecular Weight:451.52
InChIKey: YLCFOHVAOBLAIK-HNNXBMFYSA-N
SMILES: CN1C(C(N[C@@H](C)CN2CCC2)=O)=CC(C3=CC=NC(NC4=CC(OC)=CC(OC)=C4)=N3)=N1
Biological Activity: NMS-0963 (compound 1) is an inhibitor of spleen tyrosine kinase (SYK) with an oral activity and IC50 value of 3 nM. NMS-0963 inhibits BaF3-TEL/SYK cell line proliferative at 27 nM[1].
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NMS-0963 | NMS-0963 (compound 1) is an inhibitor of spleen tyrosine kinase (SYK) with an oral activity and IC50 value of 3 nM. NMS-0963 inhibits BaF3-TEL/SYK cell line proliferative at 27 nM. | |||||||||||||||||||||
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References
Keywords
