2934621-29-9
2934621-29-9
Chemical Structure
Thalidomide-5-F-6-azetidin-MeOH
- CAS No.: 2934621-29-9
- Formula:C17H16FN3O5
- Molecular Weight:361.32
InChIKey: VQWPUJJZXZBJDW-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(N4CC(CO)C4)C(F)=C3)=O
Biological Activity: Thalidomide-5-F-6-azetidin-MeOH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC FLT3/CHK1 Degrader-1 (HY-178858). PROTAC FLT3/CHK1 Degrader-1 is a potent FLT3/CHK1 degrader with anti-tumor activity[1].
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Thalidomide-5-F-6-azetidin-MeOH | Thalidomide-5-F-6-azetidin-MeOH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC FLT3/CHK1 Degrader-1 (HY-178858). PROTAC FLT3/CHK1 Degrader-1 is a potent FLT3/CHK1 degrader with anti-tumor activity. | |||||||||||||||||||||
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References
Keywords
