2944452-34-8
2944452-34-8
Chemical Structure
EGFR-IN-88
- CAS No.: 2944452-34-8
- Formula:C22H18Cl2N4O2S
- Molecular Weight:473.37
InChIKey: VIJBROPXMOLSCE-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(Cl)C=C1Cl)CSC2=NN=C(C3=CC=C4N=C(CC)C(CC)=NC4=C3)O2
Biological Activity: EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].
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EGFR-IN-88 | EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis. | |||||||||||||||||||||
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References
Keywords
