3030264-54-8
3030264-54-8
Chemical Structure
MPO-IN-9
- CAS No.: 3030264-54-8
- Formula:C18H18F3N5OS
- Molecular Weight:409.43
SMILES: O=C1C2=C(C=CN2)N(CC3=CC=CN=C3[C@H]4C[C@@H](C(F)(F)F)CCN4)C(N1)=S
Biological Activity: MPO-IN-9 is a selective inhibitor of myeloperoxidase (MPO), with an IC50 value of 3.9 nM. MPO-IN-9 inhibits MPO-mediated ROS production and protects NO-dependent vascular function by blocking MPO's chlorination and peroxidation cycles. MPO-IN-9 can be used for the study of diseases such as chronic kidney disease (CKD), non-alcoholic steatohepatitis (NASH)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MPO-IN-9 | MPO-IN-9 is a selective inhibitor of myeloperoxidase (MPO), with an IC50 value of 3.9 nM. MPO-IN-9 inhibits MPO-mediated ROS production and protects NO-dependent vascular function by blocking MPO's chlorination and peroxidation cycles. MPO-IN-9 can be used for the study of diseases such as chronic kidney disease (CKD), non-alcoholic steatohepatitis (NASH). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
