3077918-53-4
3077918-53-4
Chemical Structure
DHFR-IN-5-amino-PEG3-C2-azido
- CAS No.: 3077918-53-4
- Formula:C26H40N8O6
- Molecular Weight:560.65
InChIKey: KGWDSVNGPSUHCE-UHFFFAOYSA-N
SMILES: CCC1=NC(N)=NC(N)=C1OCCCOC(C=CC=C2)=C2CCC(NCCOCCOCCOCCN=[N+]=[N-])=O
Biological Activity: DHFR-IN-5-amino-PEG3-C2-azido is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize BION106 (HY-178728). BION106 is a potent DHFR-TS PROTAC degrader with anti-malarial activity[1].
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DHFR-IN-5-amino-PEG3-C2-azido | DHFR-IN-5-amino-PEG3-C2-azido is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize BION106 (HY-178728). BION106 is a potent DHFR-TS PROTAC degrader with anti-malarial activity. | |||||||||||||||||||||
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References
Keywords
