3115004-02-6

PKM2-IN-8 Chemical Structure
3115004-02-6

Chemical Structure

PKM2-IN-8

  • CAS No.: 3115004-02-6
  • Formula:C19H13N7O
  • Molecular Weight:355.35

InChIKey: HDZMQPHMTCBQOZ-UHFFFAOYSA-N

SMILES: O=C(CN1N=C(C2=CC=C(C=CC=C3)C3=C2)N=N1)C4=CN=C5N4C=CC=N5

Biological Activity: PKM2-IN-8 (Compound 9b) is a pyruvate kinase M2 (PKM2) inhibitor (IC50 = 0.31 μM). PKM2-IN-8 has potent antiproliferative activity against U87MG glioma cells. PKM2-IN-8 can induce early apoptosis and reduce lactate levels. PKM2-IN-8 can be used for the research of glioblastoma[1].

Cat. No. Product Name Purity Description Pricing
HY-170577 		PKM2-IN-8 PKM2-IN-8 (Compound 9b) is a pyruvate kinase M2 (PKM2) inhibitor (IC50 = 0.31 μM). PKM2-IN-8 has potent antiproliferative activity against U87MG glioma cells. PKM2-IN-8 can induce early apoptosis and reduce lactate levels. PKM2-IN-8 can be used for the research of glioblastoma.
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