348079-14-1
Chemical Structure
Fluo-3FF pentapotassium
- CAS No.: 348079-14-1
- Formula:C35H21Cl2F2K5N2O13
- Molecular Weight:981.94
IUPAC Name: (E)-2-(2-nitrobenzylidene)hydrazine-1,2-15N2-1-carboxamide-13C
InChIKey: VRZZNEZQSQRZPU-UHFFFAOYSA-I
SMILES: O=C1C=C2OC3=C(C(C4=CC(OCCOC5=C(C(F)=CC=C5N(CC(O[K])=O)CC(O[K])=O)F)=C(N(CC(O[K])=O)CC(O[K])=O)C=C4)=C2C=C1Cl)C=C(Cl)C(O[K])=C3
Biological Activity: Fluo-3FF pentapotassium is a cell-impermeant fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 μM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
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Fluo-3FF pentapotassium | Fluo-3FF pentapotassium is a cell-impermeant fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 μM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations. | |||||||||||||||||||||
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Keywords
