485815-61-0
Chemical Structure
TPU-0037C
- CAS. Nr.: 485815-61-0
- Formula:C46H72N4O9
- Molecular Weight:825.09
IUPAC Name: 2-((4E,8E,12E,16E)-2,6,10,14,18-pentahydroxy-21-(5-hydroxy-1-(4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-1,3-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-2-yl)-11,17,19-trimethylhenicosa-4,8,12,16-tetraen-1-yl)pyrrolidine-1-carboximidamide
InChIKey: UAKZHUQKPSUQEQ-RUKUQFBXSA-N
SMILES: OC(CC1N(CCC1)C(N)=N)C/C=C/C(C/C=C/C(C(/C=C/C(C/C=C(C(C(C)CCC2C(C)=CC3C(CCCC3C2(C(C4=C(CNC4=O)O)=O)C)O)O)\C)O)C)O)O
Biological Activity: TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to Lydicamycin (HY-125414). It is active against Gram-positive bacteria (MICs=0.39-3.13 μg/mL), including methicillin-resistant S. aureus strains (MIC=3.13 μg/mL), but is ineffective against Gram-negative bacteria (MICs=>50 μg/mL).
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TPU-0037C | TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to Lydicamycin (HY-125414). It is active against Gram-positive bacteria (MICs=0.39-3.13 μg/mL), including methicillin-resistant S. aureus strains (MIC=3.13 μg/mL), but is ineffective against Gram-negative bacteria (MICs=>50 μg/mL). | |||||||||||||||||||||
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Keywords
