5081-51-6
5081-51-6
Chemical Structure
Vasicinol
Synonym(s): 6-Hydroxypeganine
- CAS No.: 5081-51-6
- Formula:C11H12N2O2
- Molecular Weight:204.23
IUPAC Name: (S)-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-3,7-diol
InChIKey: WEFMOGRHGUPGMA-JTQLQIEISA-N
SMILES: O[C@H]1CCN2C1=NC3=C(C=C(O)C=C3)C2
Biological Activity: Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].
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Vasicinol | Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica. | |||||||||||||||||||||
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References
- [1]. Gao H, et al. Inhibitory effect on α-glucosidase by Adhatoda vasica Nees. Food Chem. 2008 Jun 1;108(3):965-72. [Content Brief]
- [2]. Tehreem S, et al. A UPLC-DAD-Based Bio-Screening Assay for the Evaluation of the Angiotensin Converting Enzyme Inhibitory Potential of Plant Extracts and Compounds: Pyrroquinazoline Alkaloids from Adhatoda vasica as a Case Study. Molecules. 2021 Nov 18;26(22):6971. [Content Brief]
Keywords
