518058-84-9
518058-84-9
Chemical Structure
KX1-004
- CAS No.: 518058-84-9
- Formula:C16H13FN2O2
- Molecular Weight:284.29
IUPAC Name: 5-fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide
InChIKey: TUIHIKXCMCXXJG-UHFFFAOYSA-N
SMILES: O=C(C(N1)=CC2=C1C=CC(F)=C2)NCC3=CC=CC(O)=C3
Biological Activity: KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KX1-004 | 99.75% | KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL). | ||||||||||||||||||||
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References
- [1]. Harris KC, et al. Prevention of noise-induced hearing loss with Src-PTK inhibitors. Hear Res. 2005 Oct;208(1-2):14-25. [Content Brief]
- [2]. Bielefeld EC, et al. A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing loss. Noise Health. 2005 Oct-Dec;7(29):24-30. [Content Brief]
Keywords
