530151-56-5
Chemical Structure
Bromo-PEG2-C2-azide
- CAS No.: 530151-56-5
- Formula:C6H12BrN3O2
- Molecular Weight:238.08
IUPAC Name: 1-azido-2-(2-(2-bromoethoxy)ethoxy)ethane
InChIKey: QZCKRLVDTQCBFT-UHFFFAOYSA-N
SMILES: BrCCOCCOCCN=[N+]=[N-]
Biological Activity: Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Bromo-PEG2-C2-azide | 98.70% | Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bromo-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Keywords
