56389-87-8
Chemical Structure
(2R)-Flavanomarein
- CAS No.: 56389-87-8
- Formula:C21H22O11
- Molecular Weight:450.39
IUPAC Name: (R)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one
InChIKey: DGGOLFCPSUVVHX-HIFIWIPGSA-N
SMILES: OC1=C2C(C(C[C@H](C3=CC(O)=C(C=C3)O)O2)=O)=CC=C1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
Biological Activity: (2R)-Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R)-Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2].
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(2R)-Flavanomarein | (2R)-Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R)-Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities. | |||||||||||||||||||||
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- [1]. Nan-Nan Zhang, et al. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Sci Rep. 2020 Jan 16;10(1):439. [Content Brief]
- [2]. Liang Le, et al. The protective effects of the native flavanone flavanomarein on neuronal cells damaged by 6-OHDA. Phytomedicine. 2019 Feb;53:193-204. [Content Brief]
Keywords
