566203-88-1
566203-88-1
Chemical Structure
AZD2098
- No. CAS: 566203-88-1
- Formula:C11H9Cl2N3O3S
- Molecular Weight:334.18
IUPAC Name: 2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
InChIKey: FLSMVCMSUNISFK-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=CN=C2OC)=O
Biological Activity: AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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AZD2098 | 99.91% | AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research. | ||||||||||||||||||||
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References
- [1]. Kindon N, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986. [Content Brief]
- [2]. Asher Mullard. Cancer charity sees success re-prioritizing industry's shelved compounds. Nat Rev Drug Discov. 2014 May;13(5):319-21. [Content Brief]
Keywords
