58510-66-0
58510-66-0
Chemical Structure
2′,5′-Dideoxy-5′-iodouridine
- CAS No.: 58510-66-0
- Formula:C9H11IN2O4
- Molecular Weight:338.10
IUPAC Name: 1-((2R,4S,5S)-4-hydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: JYWLLSHCWALPBJ-SHYZEUOFSA-N
SMILES: O=C(C=C1)NC(N1[C@@H]2O[C@H](CI)[C@@H](O)C2)=O
Biological Activity: 2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2′,5′-Dideoxy-5′-iodouridine | 2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
