63065-90-7
Chemical Structure
4-hydroxy DiPT hydrochloride
Synonym(s): 4-OH-DiPT hydrochloride
- CAS No.: 63065-90-7
- Formula:C16H25ClN2O
- Molecular Weight:296.84
IUPAC Name: 3-(2-(diisopropylamino)ethyl)-1H-indol-4-ol hydrochloride
InChIKey: SBBDIXSABJRYFC-UHFFFAOYSA-N
SMILES: OC1=CC=CC2=C1C(CCN(C(C)C)C(C)C)=CN2.Cl
Biological Activity: 4-hydroxy DiPT hydrochloride is an 5-HT2A agonist that induces the head-twitch response (HTR) in mice, indicating psychoactivity[1][2]. 4-hydroxy DiPT hydrochloride significantly reduced freezing responses to conditioned cues in a dose-dependent manner with a greater potency in female mice than male mice[3].
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4-hydroxy DiPT hydrochloride | 4-hydroxy DiPT hydrochloride is an 5-HT2A agonist that induces the head-twitch response (HTR) in mice, indicating psychoactivity. 4-hydroxy DiPT hydrochloride significantly reduced freezing responses to conditioned cues in a dose-dependent manner with a greater potency in female mice than male mice. | |||||||||||||||||||||
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- [1]. Rickli A, et al. Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens. Eur Neuropsychopharmacol. 2016 Aug;26(8):1327-37. [Content Brief]
- [2]. Gatch MB, et al. Discriminative Stimulus Effects of Substituted Tryptamines in Rats. ACS Pharmacol Transl Sci. 2020 Dec 29;4(2):467-471. [Content Brief]
- [3]. Kelly TJ, Bonniwell EM, Mu L, et al. Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala. Neuropsychopharmacology. 2024;49(5):854-863. [Content Brief]
Keywords
