631864-00-1
Chemical Structure
XL-844
Synonym(s): EXEL-9844
- CAS No.: 631864-00-1
- Formula:C14H17N5O2
- Molecular Weight:287.32
IUPAC Name: 1-(2-(3-aminopropoxy)phenyl)-3-(pyrazin-2-yl)urea
InChIKey: UVSSZSQSZGKMAL-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=CN=C1)NC2=CC=CC=C2OCCCN
Biological Activity: XL-844 (EXEL-9844) is an inhibitor of Chk1 and Chk2. XL-844 exhibits antineoplastic activity. XL-844 can result in tumor cell apoptosis through inhibition of cell cycle arrest. XL-844 inhibits VEGFR1 and VEGFR3. XL-844 can be studied in anti-cancer research[1].
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XL-844 | XL-844 (EXEL-9844) is an inhibitor of Chk1 and Chk2. XL-844 exhibits antineoplastic activity. XL-844 can result in tumor cell apoptosis through inhibition of cell cycle arrest. XL-844 inhibits VEGFR1 and VEGFR3. XL-844 can be studied in anti-cancer research. | |||||||||||||||||||||
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Keywords