749179-13-3
Chemical Structure
CS-722 Free base
- CAS No.: 749179-13-3
- Formula:C16H19ClN2O4
- Molecular Weight:338.79
IUPAC Name: (R)-4-chloro-2-(2-hydroxy-3-morpholinopropyl)-5-phenylisoxazol-3(2H)-one
InChIKey: NINUODAOHUBAAQ-CYBMUJFWSA-N
SMILES: ClC1=C(C2=CC=CC=C2)ON(C[C@H](O)CN3CCOCC3)C1=O
Biological Activity: CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents[2].
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CS-722 Free base | CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex. CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents. | |||||||||||||||||||||
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- [1]. Tanabe M, et al. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313(3):187-9. [Content Brief]
- [2]. Marszalec W, et al. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119(1):126-32. [Content Brief]
Keywords
