940057-42-1
940057-42-1
Chemical Structure
JNK-IN-16
- CAS No.: 940057-42-1
- Formula:C18H14N4O
- Molecular Weight:302.33
InChIKey: ZGJYGQLGSXWEMY-UHFFFAOYSA-N
SMILES: OC1=CC=C(C=C1)CC2=NN=C3N2N=C(C=C3)C4=CC=CC=C4
Biological Activity: JNK-IN-16 is a c-Met and JNK inhibitor with nanomolar potency, with IC50 values of 120 nM and 72 nM, respectively. JNK-IN-16 can be used for cancer research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JNK-IN-16 | 99.82% | JNK-IN-16 is a c-Met and JNK inhibitor with nanomolar potency, with IC50 values of 120 nM and 72 nM, respectively. JNK-IN-16 can be used for cancer research. | ||||||||||||||||||||
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References
- [1]. Albrecht BK, et al. Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase. J Med Chem. 2008;51(10):2879-2882. [Content Brief]
- [2]. Yu-Ping Yang, et al. Statistical molecular identification of kinase inhibitors to disrupt c-Jun N-terminal protein kinase involved in paraquat-mediated toxicological effects. Journal of Chemometrics. 2017;e2905.
Keywords
