94736-09-1
94736-09-1
Chemical Structure
dUTP sodium
Synonym(s): 2'-Deoxyuridine-5'-triphosphate sodium salt
- CAS No.: 94736-09-1
- Formula:C9H15N2O14P3.xNa
- Molecular Weight:N/A
SMILES: OP(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C=C2)=O)=O)O1)(OP(O)(OP(O)(O)=O)=O)=O.[x].[Na]
Biological Activity: dUTP sodium is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver[1][2][3][4].
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dUTP sodium | dUTP sodium is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver. | |||||||||||||||||||||
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References
- [1]. Nayun Kim, et al. dUTP incorporation into genomic DNA is linked to transcription in yeast. Nature. 2009 Jun 25;459(7250):1150-3. [Content Brief]
- [2]. Longo, M. C., et al., (1990). Use of uracil DNA glycosylase to control carry-over contamination in polymerase chain reactions. Gene, 93(1), 125–128. [Content Brief]
- [3]. Wisdom, G. B., & Orsi, B. A. (1969). The purification and properties of cytidine aminohydrolase from sheep liver. European journal of biochemistry, 7(2), 223–230. [Content Brief]
- [4]. Grafstrom, R. H., et al., (1978). The incorporation of uracil into animal cell DNA in vitro. Cell, 15(1), 131–140. [Content Brief]
Keywords
