947620-48-6
947620-48-6
Chemical Structure
Lotamilast
Synonym(s): RVT-501; E6005
- CAS No.: 947620-48-6
- Formula:C26H24N4O5
- Molecular Weight:472.49
IUPAC Name: methyl 4-((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)carbamoyl)benzoate
InChIKey: BBTFKAOFCSOZMB-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(OC)=O)C=C1)NC2=CC=CC(C3=C4C(C=C(OC)C(OC)=C4)=NC(NC)=N3)=C2
Biological Activity: Lotamilast (RVT-501; E6005) is a selective phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.8 nM.
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Lotamilast | 98.0% | Lotamilast (RVT-501; E6005) is a selective phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.8 nM. | ||||||||||||||||||||
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Lotamilast (Standard) | ≥98% | Lotamilast (Standard) is the analytical standard of Lotamilast. This product is intended for research and analytical applications. Lotamilast (RVT-501; E6005) is a selective phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.8 nM. | ||||||||||||||||||||
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Keywords
