948298-76-8
948298-76-8
Chemical Structure
2-Chloro-N6-(2-hydroxyethyl)adenosine
- CAS No.: 948298-76-8
- Formula:C12H16ClN5O5
- Molecular Weight:345.74
IUPAC Name: (2R,3R,4S,5R)-2-(2-chloro-6-((2-hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChIKey: RDZDHAJEWMXENA-IOSLPCCCSA-N
SMILES: ClC1=NC2=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C(NCCO)=N1
Biological Activity: 2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Chloro-N6-(2-hydroxyethyl)adenosine | 2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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