955977-50-1
955977-50-1
Chemical Structure
PI-3065
- CAS No.: 955977-50-1
- Formula:C27H31FN6OS
- Molecular Weight:506.64
IUPAC Name: 4-(6-((4-(cyclopropylmethyl)piperazin-1-yl)methyl)-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin-4-yl)morpholine
InChIKey: YDNOHCOYQVZOMC-UHFFFAOYSA-N
SMILES: FC(C=CC1=C2C=CN1)=C2C3=NC4=C(SC(CN5CCN(CC6CC6)CC5)=C4)C(N7CCOCC7)=N3
Biological Activity: PI-3065 is a potent inhibitor of PI3K p110δ, with IC50 and Ki values of 5 nM and 1.5 nM, and exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PI-3065 | 98.97% | PI-3065 is a potent inhibitor of PI3K p110δ, with IC50 and Ki values of 5 nM and 1.5 nM, and exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM. | ||||||||||||||||||||
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Keywords
