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Art. -Nr.: HY-100823

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(1S,3R)-ACPD

(1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells.

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CAS. Nr.: 111900-32-4
Formel: C₇H₁₁NO₄
Molecular Weight:173.17

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(1S,3R)-ACPD Chemical Structure

CAS. Nr.: 111900-32-4

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

(1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells^[1].

Alle mGluR Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	15 μM Compound: (+/-)5	Activity tested at cloned rat Metabotropic glutamate receptor 1 expressed in Chinese Hamster Ovary (CHO) cells Activity tested at cloned rat Metabotropic glutamate receptor 1 expressed in Chinese Hamster Ovary (CHO) cells	[PMID: 12825948]
CHO	EC₅₀	2 μM Compound: (+/-)5	Activity tested at cloned rat mGluR2 receptor expressed in Chinese Hamster Ovary (CHO) cells Activity tested at cloned rat mGluR2 receptor expressed in Chinese Hamster Ovary (CHO) cells	[PMID: 12825948]
CHO	EC₅₀	23 μM Compound: (+/-)5	Activity tested at cloned rat Metabotropic glutamate receptor 5 expressed in Chinese Hamster Ovary (CHO) cells Activity tested at cloned rat Metabotropic glutamate receptor 5 expressed in Chinese Hamster Ovary (CHO) cells	[PMID: 12825948]
CHO	EC₅₀	800 μM Compound: (+/-)5	Activity tested at cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cells Activity tested at cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cells	[PMID: 12825948]
HEK293	EC₅₀	>100 μM Compound: 16	Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inactive Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inactive	[PMID: 15801843]
HEK293	EC₅₀	18 μM Compound: 1/ (1S,3R -)-ACPD	Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation	[PMID: 9301676]
HEK293	EC₅₀	9.3 μM Compound: 1/ (1S,3R -)-ACPD	Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation	[PMID: 9301676]
HEK293	EC₅₀	>1000 μM Compound: 1/ (1S,3R -)-ACPD	Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulation	[PMID: 9301676]

Chemical Information

CAS. Nr. 111900-32-4
Molecular Weight 173.17
Formel C₇H₁₁NO₄
SMILES

O=C([C@@]1(N)C[C@H](C(O)=O)CC1)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. A E Bandrowski, et al. Metabotropic glutamate receptors modify ionotropic glutamate responses in neocortical pyramidal cells and interneurons. Exp Brain Res. 2001 Jan;136(1):25-40. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biologische Aktivität
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(1S,3R)-ACPD

Alle mGluR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

(1S,3R)-ACPD Related Classifications

HY-100823 Related Classifications